Melanotan II 10mg Research Peptide Canada

Melanotan 2 (MT‑2) is a synthetic analog of the body’s natural melanocyte‑stimulating hormone (MSH). By activating melanocortin receptors, it promotes increased melanin production, leading to a deeper tanning effect even with limited sun exposure.

In addition to its role in pigmentation, Melanotan 2 has been explored for its potential influence on appetite regulation and sexual function, due to its interaction with specific neural pathways involved in these processes.

Key Research Areas & Mechanistic Highlights

🎨 Pigmentation & Melanin Production

• Synthetic analog of endogenous α‑MSH
• Activates MC1R receptors on melanocytes
• Studied for its ability to increase eumelanin synthesis
• Used in research exploring UV‑independent pigmentation pathways

🧠 Neural Pathways & Receptor Activity

• Interacts with multiple melanocortin receptors (MC1R–MC5R)
• Examined for its influence on CNS signaling networks
• Studied in relation to neuroendocrine communication and behavioral pathways

🍽️ Appetite & Energy Regulation

• Investigated for potential effects on satiety‑related signaling
• Explored in metabolic research involving melanocortin‑mediated pathways
• Used to study mechanisms related to energy balance and feeding behavior

🔥 Sexual Function & Arousal Pathways

• Preclinical interest due to interactions with MC3R and MC4R
• Studied for its role in neural circuits associated with sexual response
• Considered a model compound for understanding melanocortin‑linked arousal mechanisms.

Melanotan II is widely used in melanocortin‑receptor research, particularly involving MC1R, MC3R, MC4R, and MC5R signaling in controlled in‑vitro systems.

Key research applications include:

• Receptor‑binding assays — used to evaluate affinity and receptor‑subtype selectivity across the melanocortin family.
• Intracellular signaling studies — supports research into cAMP accumulation, PKA activation, and downstream transcriptional responses.
• Structure–activity analysis — applied in comparisons of cyclic vs. linear melanocortin analogs to evaluate stability and receptor bias.
• Peptide‑stability modeling — used to study enzymatic degradation and cyclic‑peptide resistance to proteolysis.
• Analytical method development — suitable for validating chromatographic separation of cyclic heptapeptides.

• Type: Cyclic heptapeptide melanocortin analog.
• Form: Lyophilized powder (10mg).
• Identity: Verified via MS and HPLC/UPLC.
• Biochemical Notes:
• Cyclic structure enhances stability and receptor affinity.
• Solubility varies with pH; performs best in mildly acidic buffers.
• Stability:
• Stable in dry form; sensitive to hydrolysis and oxidation in solution.
• Avoid prolonged exposure to elevated temperatures.

• Store at –20°C, protected from humidity and light.
• Reconstituted solutions should be stored at 2–8°C and used promptly.
• Avoid repeated freeze–thaw cycles.

• COA includes MS identity, HPLC purity, solvent system, and lot traceability.
• RUO‑only; not for human or veterinary use.

Melanotan II is supplied for laboratory research only. Not for human or veterinary use. No therapeutic, metabolic, or performance‑related claims are made or implied.