🧬 SS‑31 (50mg) — High‑Purity Mitochondria‑Targeted Tetrapeptide for Cardiolipin‑Binding, Oxidative‑Stress & Cellular‑Bioenergetics Research (Canada‑Wide)

SS‑31 (50mg) is a high‑purity, research‑grade mitochondria‑targeted tetrapeptide widely referenced in Canadian laboratory environments for studies involving cardiolipin interactions, mitochondrial‑membrane stabilization, oxidative‑stress modulation, and cellular‑bioenergetics regulation.

Also known as Elamipretide, SS‑31 is engineered to selectively associate with cardiolipin‑rich inner mitochondrial membranes, making it a valuable tool for in‑vitro and preclinical research exploring mitochondrial dysfunction, ROS‑associated pathways, and bioenergetic resilience.

Its compact structure, strong analytical visibility, and predictable behavior in controlled systems make SS‑31 a preferred peptide for Canadian researchers studying mitochondrial integrity, electron‑transport chain (ETC) dynamics, and cellular‑stress adaptation.

🔍 What Is SS‑31?

SS‑31 is a synthetic aromatic‑cationic tetrapeptide designed to selectively target the inner mitochondrial membrane (IMM) through high‑affinity binding to cardiolipin, a phospholipid essential for mitochondrial structure and function.

In research settings, SS‑31 is used to study:

• Cardiolipin–peptide interactions

• Mitochondrial‑membrane stabilization

• Electron‑transport chain (ETC) efficiency

• Oxidative‑stress and ROS‑associated pathways

• Cellular‑bioenergetics and ATP‑production models

• Mitochondrial‑dysfunction and stress‑response signaling

🔬 Scientific Context

SS‑31 is frequently referenced in studies involving:

• Mitochondrial permeability and membrane potential

• Cardiolipin oxidation and lipid‑peroxidation models

• ETC complex stability and electron‑leak dynamics

• Cellular‑resilience under metabolic or oxidative stress

• Comparative mitochondrial‑targeted peptide research

Its unique ability to localize to mitochondria without requiring membrane potential makes SS‑31 a powerful tool for bioenergetics and mitochondrial‑mechanism research.

📡 Mechanistic Overview

🔷 Cardiolipin Binding & Membrane Stabilization

• Selectively associates with cardiolipin‑rich IMM regions

• Supports research involving mitochondrial‑membrane integrity

• Used in models examining lipid‑peroxidation and membrane destabilization

🔶 Oxidative‑Stress & ROS‑Linked Pathways

• Applied in studies involving reactive oxygen species (ROS) markers

• Supports investigations into oxidative‑stress adaptation

• Used in multi‑pathway redox‑biology modeling

🔵 Electron‑Transport Chain (ETC) Dynamics

• Examined in ETC‑complex stability and electron‑leak studies

• Supports mapping of ATP‑production efficiency

• Used in comparative mitochondrial‑function assays

🟣 Cellular‑Bioenergetics & Stress‑Response

• Referenced in metabolic‑stress and mitochondrial‑dysfunction models

• Supports peptide‑mediated resilience and adaptation research

• Used in multi‑axis bioenergetic investigations

🧱 Structural Overview

🧪 Molecular Composition

• Type: Synthetic aromatic‑cationic tetrapeptide

• Form: Lyophilized powder (50mg fill)

• Identity: Verified via MS and HPLC/UPLC

• Origin: Designed for mitochondrial targeting

🧬 Functional Domains

• Cationic domain: Facilitates mitochondrial localization

• Aromatic domain: Enables cardiolipin binding

• Bioenergetic domain: Supports ETC‑linked research

🎯 Pathway Targets

• Cardiolipin‑associated mitochondrial pathways

• Oxidative‑stress and redox‑state markers

• ETC‑complex stability and ATP‑production networks

• Mitochondrial‑dysfunction and stress‑response cascades

• Peptide–lipid and peptide–protein interaction models

🔬 Research Focus Areas

SS‑31 is referenced in research involving:

• Mitochondrial‑membrane and cardiolipin‑interaction studies

• Oxidative‑stress and ROS‑marker assays

• ETC‑complex stability and electron‑transport modeling

• Cellular‑bioenergetics and ATP‑production analysis

• Mitochondrial‑dysfunction and metabolic‑stress investigations

• Comparative mitochondrial‑targeted peptide research

Its mechanistic specificity makes it suitable for advanced mitochondrial‑biology research across Canada.

🧊 Stability & Biochemical Notes

• Highly stable in lyophilized form

• Sensitive to oxidation and hydrolysis once reconstituted

• Avoid prolonged exposure to room temperature

• Avoid repeated freeze–thaw cycles

• Use sterile technique during preparation

❄️ Storage & Handling

• Store lyophilized peptide at –20°C, protected from light and humidity

• Reconstituted solutions should be stored at 2–8°C

• Use promptly after reconstitution

• Maintain sterile technique during preparation

🇨🇦 Optimized for Canadian Research Environments

BlueNexLabs supplies SS‑31 to research institutions across:

Vancouver • Toronto • Montreal • Calgary • Edmonton • Ottawa • Canada‑Wide

Offering:

• High‑purity, COA‑verified peptide materials

• Audit‑safe RUO labeling

• Fast, Canada‑wide fulfillment

• Research‑focused support for mitochondrial and oxidative‑stress studies

📄 Documentation & COA Visibility

Each batch includes:

• MS identity confirmation

• HPLC purity profile

• Solvent system details

• RUO‑only designation

All documentation is structured for audit‑safe compliance and laboratory reproducibility.

⚠️ Compliance Notice

SS‑31 is supplied for laboratory research only. Not for human or veterinary use. No therapeutic, metabolic, or performance‑related claims are made or implied.