🧬 AICAR — Research Compound

High‑Purity AMPK‑Targeting Research Compound for Cellular Energy & Metabolic‑Signaling Studies (Canada)

AICAR (5‑Aminoimidazole‑4‑carboxamide ribonucleotide) is a well‑characterized research compound widely utilized in laboratory studies involving AMP‑activated protein kinase (AMPK) signaling and cellular energy‑regulation pathways. As an AMP analog, AICAR is incorporated into experimental systems designed to model how cells detect and adapt to changes in energy availability.

Supplied by BlueNexLabs, AICAR is provided as a high‑purity research compound with COA‑verified analytical consistency and audit‑safe Research‑Use‑Only (RUO) labeling, supporting advanced experimental workflows in Canadian research environments.

🔬 Overview of AICAR in Research Settings

AICAR is commonly used in laboratory models to investigate cellular energy‑sensing mechanisms and bioenergetic adaptation pathways.

In controlled research environments, AICAR is frequently referenced in studies examining:

• AMP‑activated protein kinase (AMPK) pathway signaling

• Cellular energy‑homeostasis regulation

• Metabolic‑stress and energy‑depletion models

• Mitochondrial activity and bioenergetic function

• Gene expression related to energy‑regulation pathways

Its role as an AMP analog enables controlled study of intracellular signaling associated with energy balance.

🧪 What Is AICAR?

AICAR is a synthetic research compound structurally similar to adenosine monophosphate (AMP), designed for laboratory investigations involving:

• AMPK activation pathways

• Cellular energy‑sensing mechanisms

• Bioenergetic signaling networks

Within experimental systems, AICAR supports analysis of how cells respond to shifts in metabolic demand and energy availability.

In research contexts, AICAR is applied in studies involving:

• Signal transduction related to energy regulation

• Cellular adaptation to metabolic stress

• Mitochondrial function and efficiency

• Pathway‑specific vs. integrated metabolic responses

📡 Mechanistic Research Overview (Audit‑Safe)

🔵 AMPK‑Linked Signaling

• Referenced in studies of cellular energy‑sensing pathways

• Used in models examining metabolic‑stress signaling

• Supports investigation of intracellular regulatory cascades

🟠 Metabolic Pathway Modeling

• Applied in research exploring glucose and lipid metabolism models

• Supports analysis of pathway‑level signaling interactions

• Used in comparative metabolic studies

🟣 Mitochondrial & Bioenergetic Research

• Examined in studies involving energy production and utilization

• Supports research on mitochondrial signaling pathways

• Used in bioenergetic adaptation models

🔗 Cellular Stress Response

• Enables modeling of energy‑depletion conditions

• Supports studies on adaptive signaling behavior

• Used in pathway‑response and regulatory mechanism analysis

🧱 Molecular & Chemical Characteristics

Compound Name: AICAR (5‑Aminoimidazole‑4‑carboxamide ribonucleotide)
Molecular Weight: ~338.2 g/mol
CAS Number: 2627‑69‑2
Form: Powder
Purity: ≥99%

Structural & Biochemical Notes

• Functions as an AMP analog in experimental systems

• Demonstrates consistent analytical performance in laboratory workflows

• Suitable for signaling pathway and metabolic‑modeling applications

• Sensitive to environmental conditions depending on handling and preparation

🔬 Research Focus Areas

AICAR is widely referenced in laboratory research involving:

• AMPK pathway activation studies

• Cellular energy‑regulation modeling

• Metabolic‑stress and adaptation research

• Mitochondrial signaling and function analysis

• Bioenergetic pathway integration studies

Its role in energy‑sensing mechanisms supports a broad range of controlled experimental applications.

❄️ Storage & Handling Guidelines

• Store in a cool, dry environment, protected from light and moisture

• Maintain appropriate laboratory storage conditions per protocol

• Avoid prolonged exposure to ambient environmental factors

• Use proper laboratory handling techniques to preserve integrity

📄 Certificate of Analysis & Documentation

Each batch of AICAR supplied by BlueNexLabs includes audit‑ready documentation:

• Identity and purity verification

• Manufacturer testing results

• Research‑Use‑Only (RUO) designation

🔗 Learn About Our Testing Standards
🔗 Explore the BlueNexLabs Research Compound Catalog

🇨🇦 Supplied for Canadian Research Laboratories

BlueNexLabs supplies AICAR research compound to laboratories across Vancouver, Toronto, Montreal, Calgary, Edmonton, Ottawa, and throughout Canada.

Why Researchers Choose BlueNexLabs

🇨🇦 Canada‑wide domestic shipping
🧪 Audit‑safe RUO labeling
⚡ Fast fulfillment & responsive support
🔬 Research‑focused compound catalog

⚠️ Compliance Notice

This product is supplied strictly for laboratory research use only (RUO).
Not for human or veterinary use.
No medical, therapeutic, metabolic, diagnostic, or performance‑related claims are made or implied.