Is the C-terminus always an amide on research peptides?

No. Acid and amide are both possible. Use the form written on the lot file. If it is absent, do not choose one.

Does the C-terminus appear in the shop URL?

No. The URL carries a catalogue name and often a milligram size. End-group chemistry belongs on the sequence note or the report.

Glossary · 2026-09-24

Scientific lead: Alice Kay, Ph.D.

C-terminus of a peptide chain

The C-terminus is the end of the chain opposite the N-terminus. It may be a carboxylic acid or an amide. Those forms are different species, so a calculated mass has to follow the form the report names. Amidation is the glossary entry for the amide case. It is not a purity unit.

Do not flip a sequence to put the C-terminus first, and do not assume an amide because a trade name sounds modified. Read the species line on the PDF, then the sequence as published. For the structure discussion, see peptide structure and stability. Research use only.

Published lot files for this catalogue are indexed in the certificates library. This definition does not add a report, and it does not assign a task identifier. Research use only.

Frequently asked questions

Is the C-terminus always an amide on research peptides?: No. Acid and amide are both possible. Use the form written on the lot file. If it is absent, do not choose one.
Does the C-terminus appear in the shop URL?: No. The URL carries a catalogue name and often a milligram size. End-group chemistry belongs on the sequence note or the report.

Research use only. BlueNex Labs does not provide medical or veterinary advice. Confirm your institution’s policies before purchase. How a comparison or class note is checked sits on documentation standards. The biochemist of record is Alice Kay, Ph.D.