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BlueNex Labs

Research · 2025-09-21

Scientific lead: Alice Kay, Ph.D.

What is PT-141? Melanocortin ligand note

Direct answer

PT-141 (bremelanotide) is a cyclic alpha-MSH analogue discussed as a melanocortin-receptor ligand in central-nervous-system laboratory models. It is not a Melanotan listing.

Scope

Cognitive & neuroscience models. Sleep-architecture and neuroendocrine peptides discussed in laboratory literature.

Reviewer: Alice Kay, Ph.D., scientific lead. This note does not claim that the reviewer authored any cited paper.

PT-141 Research Overview

PT-141, also called bremelanotide, is a cyclic alpha-MSH analog discussed as a melanocortin-receptor ligand in central-nervous-system models. It is catalogued separately from Melanotan I and Melanotan II.

This page provides laboratory-focused information for PT-141. Content is intended for research use only and should be read with the published documentation and analytical data.

PT-141 research peptide vial label for laboratory peptide research

> Research-use notice: This article is educational laboratory context only. It is not medical advice. No dosing, administration, or human-use guidance is provided. BlueNex Labs research-use-only products are not intended for human or veterinary use.

PT-141 is the research name used for bremelanotide, a cyclic peptide analogue of alpha-melanocyte-stimulating hormone. Papers discuss it as a ligand at melanocortin receptors in central-nervous-system and neuroendocrine models. This page is a research guide. The catalogue SKU is the PT-141 10 mg product page.

Structure

Laboratory descriptions distinguish PT-141 from neighbouring melanocortin peptides:

  • A cyclic heptapeptide scaffold related to alpha-MSH, not the linear tripeptide KPV

  • A different catalogue identity from Melanotan I and from Melanotan II 10 mg

  • Sequence and ring closure that belong on the lot report and the vial label

  • No shared certificate with those other SKUs

The Melanotan receptor overview covers Melanotan analogues. It is not a substitute for this PT-141 note.

Mechanisms discussed in research settings

Literature commonly places PT-141 in:

  • Melanocortin-receptor binding assays, including receptors discussed in central-nervous-system models

  • Peptide-receptor interaction work that compares cyclic and linear alpha-MSH analogues

  • Neuroendocrine signalling maps that stay inside the assay system

  • Structure-activity comparisons that do not transfer to a personal-use claim

This article does not restate human-use indications. Receptor occupancy in a paper is not an instruction.

Cluster navigation

RUO

Research use only. Not for human or veterinary use. No administration guidance is provided.

References

This note does not add a separate citation list. Named papers, when the body links them, stay in the text above.

Research use only. BlueNex Labs does not provide medical or veterinary advice. Confirm your institution’s policies before purchase. Lot-file rules for this note are on the documentation standards page. Scientific lead: Alice Kay, Ph.D.