AICAR 50mg Research Material Canada

AICAR for AMPK Signalling, Cellular Energy Research & Metabolic Pathway Studies

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide), also known as Acadesine in scientific literature, is a well-established biochemical research compound used extensively in laboratory investigations focused on AMP-activated protein kinase (AMPK) signalling, cellular energy sensing, and metabolic pathway regulation.

As a synthetic adenosine nucleotide analogue, AICAR is frequently utilized in controlled research models designed to examine how cells detect fluctuations in energy availability and respond through intracellular signalling networks.

BlueNex Labs supplies AICAR research compound with analytical documentation and Research-Use-Only (RUO) labelling for qualified laboratory and scientific research applications throughout Canada.

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a synthetic purine nucleotide analogue that has become an important tool compound in molecular biology and biochemical research.

Within laboratory environments, AICAR is primarily studied because of its relationship with cellular energy regulation pathways, particularly those involving AMPK, a conserved protein kinase involved in cellular responses to changes in energy status.

Researchers use AICAR-containing experimental systems to investigate:

• Intracellular energy-sensing mechanisms
• AMP-related signalling pathways
• Cellular adaptation responses
• Metabolic pathway communication
• Bioenergetic regulation
• Mitochondrial signalling networks

AICAR serves as a valuable research model for studying how molecular signals influence cellular behaviour under different experimental conditions.

AICAR is widely referenced in scientific research involving cellular signalling, metabolism, and molecular regulation.

Common research areas include:

AMPK Signalling Pathway Research

AMP-activated protein kinase (AMPK) functions as an important cellular energy sensor studied across many areas of molecular biology.

AICAR is commonly used in experimental models investigating:

• AMPK-associated signalling cascades
• Energy availability sensing mechanisms
• Intracellular phosphorylation events
• Regulation of downstream signalling pathways
• Cellular responses to altered energy states

Researchers use AICAR as a biochemical tool to better understand relationships between energy signals and cellular regulation.

Cellular Energy & Bioenergetic Research

Cellular energy balance involves complex interactions between nutrient availability, molecular signalling, and metabolic pathways.

AICAR is studied in laboratory models examining:

• Cellular energy homeostasis
• ATP-related signalling mechanisms
• Bioenergetic adaptation processes
• Energy stress response pathways
• Metabolic communication between cellular systems

These studies help researchers characterize how cells coordinate energy-related processes at the molecular level.

Mitochondrial Function & Metabolic Signalling Studies

Mitochondria play a central role in cellular energy production and metabolic signalling.

Research involving AICAR may include investigations into:

• Mitochondrial signalling pathways
• Cellular respiration models
• Energy utilization mechanisms
• Metabolic adaptation responses
• Molecular pathways associated with mitochondrial activity

AICAR provides researchers with a controlled compound for studying interactions between energy sensing and cellular function.

Metabolic Pathway Research Models

AICAR is frequently included in laboratory investigations exploring complex metabolic networks.

Research applications may include:

• Glucose metabolism pathway studies
• Lipid metabolism signalling research
• Nutrient-response modelling in energy-sensing assays

AICAR is an AMPK-pathway research reagent. It is not a performance or metabolic-health product.

• Store lyophilized material at −20 °C, protected from light and moisture
• Avoid repeated freeze–thaw cycles; aliquot according to your laboratory SOP

Batch Certificates of Analysis are listed in the certificates library when published. Match vial size and lot notes before assigning a lot to an assay.

Research use only. Not for human or veterinary use. No medical, cosmetic, or performance claims are made or implied.