SS-31 10mg — Published Lot COA

SS‑31 is a research‑grade mitochondria‑targeted tetrapeptide widely referenced in Canadian laboratory environments for studies involving cardiolipin interactions, mitochondrial‑membrane stabilization, oxidative‑stress modulation, and cellular‑bioenergetics regulation.

BlueNexLabs supplies SS-31 peptide as a 10mg lyophilized fill. The published lot report names this sample. Research Use Only (RUO) designation applies.

Also known as Elamipretide, SS‑31 is engineered to selectively associate with cardiolipin‑rich inner mitochondrial membranes, making it a valuable tool for in‑vitro and preclinical research exploring mitochondrial dysfunction, ROS‑associated pathways, and bioenergetic resilience.

Its compact structure, strong analytical visibility, and predictable behavior in controlled systems make SS‑31 a commonly referenced peptide in Canadian laboratory studies of mitochondrial integrity, electron‑transport chain (ETC) dynamics, and cellular‑stress adaptation.

SS‑31 is a synthetic aromatic‑cationic tetrapeptide designed to selectively target the inner mitochondrial membrane (IMM) through high‑affinity binding to cardiolipin, a phospholipid essential for mitochondrial structure and function.

In research settings, SS‑31 is used to study:

• Cardiolipin–peptide interactions
• Mitochondrial‑membrane stabilization
• Electron‑transport chain (ETC) efficiency
• Oxidative‑stress and ROS‑associated pathways
• Cellular‑bioenergetics and ATP‑production models
• Mitochondrial‑dysfunction and stress‑response signaling

🔬 Scientific Context

SS‑31 is frequently referenced in studies involving:

• Mitochondrial permeability and membrane potential
• Cardiolipin oxidation and lipid‑peroxidation models
• ETC complex stability and electron‑leak dynamics
• Cellular‑resilience under metabolic or oxidative stress
• Comparative mitochondrial‑targeted peptide research

Its unique ability to localize to mitochondria without requiring membrane potential makes SS‑31 a powerful tool for bioenergetics and mitochondrial‑mechanism research.

🔷 Cardiolipin Binding & Membrane Stabilization

• Selectively associates with cardiolipin‑rich IMM regions
• Supports research involving mitochondrial‑membrane integrity
• Used in models examining lipid‑peroxidation and membrane destabilization

• Applied in studies involving reactive oxygen species (ROS) markers
• Supports investigations into oxidative‑stress adaptation
• Used in multi‑pathway redox‑biology modeling

• Examined in ETC‑complex stability and electron‑leak studies
• Supports mapping of ATP‑production efficiency
• Used in comparative mitochondrial‑function assays

• Referenced in metabolic‑stress and mitochondrial‑dysfunction models
• Supports peptide‑mediated resilience and adaptation research
• Used in multi‑axis bioenergetic investigations

🧪 Molecular Composition

• Type: Synthetic aromatic‑cationic tetrapeptide
• Form: Lyophilized powder (10mg fill)
• Identity: Verified via MS and HPLC/UPLC
• Origin: Designed for mitochondrial targeting

• Cationic domain: Facilitates mitochondrial localization
• Aromatic domain: Enables cardiolipin binding
• Bioenergetic domain: Supports ETC‑linked research

• Cardiolipin‑associated mitochondrial pathways
• Oxidative‑stress and redox‑state markers
• ETC‑complex stability and ATP‑production networks
• Mitochondrial‑dysfunction and stress‑response cascades
• Peptide–lipid and peptide–protein interaction models

SS-31 is referenced in research on cardiolipin-associated mitochondrial membranes, electron-transport assays, and oxidative-stress markers. Catalog vials are research-use only; 10 mg and 50 mg fills have separate lots when both exist.

• Store lyophilized material at –20 °C, protected from light and moisture
• Reconstituted solutions: 2–8 °C, short-term laboratory use only
• Avoid repeated freeze–thaw cycles; use sterile technique

The published 10 mg Certificate of Analysis is in the certificates library. That report names this 10 mg sample and does not document the SS-31 50mg listing. Match vial size and lot notes before assigning a report to an assay.

Research-use only. Not for human or veterinary use. No medical, cosmetic, or performance claims are made or implied.

The 50 mg fill is a separate catalog listing: SS-31 50mg.