SS-31 50mg

SS‑31 is a research‑grade mitochondria‑targeted tetrapeptide widely referenced in Canadian laboratory environments for studies involving cardiolipin interactions, mitochondrial‑membrane stabilization, oxidative‑stress modulation, and cellular‑bioenergetics regulation.

BlueNex Labs supplies SS-31 peptide as a 50 mg lyophilized fill under a Research Use Only (RUO) designation. No lot report is published for this SKU yet.

Also known as Elamipretide, SS‑31 is engineered to selectively associate with cardiolipin‑rich inner mitochondrial membranes, making it a valuable tool for in‑vitro and preclinical research exploring mitochondrial dysfunction, ROS‑associated pathways, and bioenergetic resilience.

Its compact structure, strong analytical visibility, and predictable behaviour in controlled systems make SS‑31 a commonly referenced peptide in Canadian laboratory studies of mitochondrial integrity, electron‑transport chain (ETC) dynamics, and cellular‑stress adaptation.

SS‑31 is a synthetic aromatic‑cationic tetrapeptide designed to selectively target the inner mitochondrial membrane (IMM) through high‑affinity binding to cardiolipin, a phospholipid essential for mitochondrial structure and function.

In research settings, SS‑31 is used to study:

• Cardiolipin–peptide interactions
• Mitochondrial‑membrane stabilization
• Electron‑transport chain (ETC) efficiency
• Oxidative‑stress and ROS‑associated pathways
• Cellular‑bioenergetics and ATP‑production models
• Mitochondrial‑dysfunction and stress‑response signalling

Scientific Context

SS‑31 is frequently referenced in studies involving:

• Mitochondrial permeability and membrane potential
• Cardiolipin oxidation and lipid‑peroxidation models
• ETC complex stability and electron‑leak dynamics
• Cellular‑resilience under metabolic or oxidative stress
• Comparative mitochondrial‑targeted peptide research

Its unique ability to localize to mitochondria without requiring membrane potential makes SS‑31 a powerful tool for bioenergetics and mitochondrial‑mechanism research.

🔷 Cardiolipin Binding & Membrane Stabilization

• Selectively associates with cardiolipin‑rich IMM regions
• Supports research involving mitochondrial‑membrane integrity
• Used in models examining lipid‑peroxidation and membrane destabilization

• Applied in studies involving reactive oxygen species (ROS) markers
• Supports investigations into oxidative‑stress adaptation
• Used in multi‑pathway redox‑biology modelling

• Examined in ETC‑complex stability and electron‑leak studies
• Supports mapping of ATP‑production efficiency
• Used in comparative mitochondrial‑function assays

• Referenced in metabolic‑stress and mitochondrial‑dysfunction models
• Supports peptide‑mediated resilience and adaptation research
• Used in multi‑axis bioenergetic investigations

Molecular Composition

• Type: Synthetic aromatic‑cationic tetrapeptide
• Form: Lyophilized powder (50 mg fill)
• Identity: No published lot report is listed for this 50 mg SKU
• Origin: Designed for mitochondrial targeting

• Cationic domain: Facilitates mitochondrial localization
• Aromatic domain: Enables cardiolipin binding
• Bioenergetic domain: Supports ETC‑linked research

• Cardiolipin‑associated mitochondrial pathways
• Oxidative‑stress and redox‑state markers
• ETC‑complex stability and ATP‑production networks
• Mitochondrial‑dysfunction and stress‑response cascades
• Peptide–lipid and peptide–protein interaction models

SS-31 is referenced in research on cardiolipin-associated mitochondrial membranes, electron-transport assays, and oxidative-stress markers. Catalogue vials are research use only; 10 mg and 50 mg fills have separate lots when both exist.

• Store lyophilized material at −20 °C, protected from light and moisture
• Avoid repeated freeze–thaw cycles; aliquot according to your laboratory SOP

No Certificate of Analysis is published for this 50 mg SKU. The 10 mg report in the certificates library names a different vial and does not document this fill. The separate listing is SS-31 10 mg. Match vial size and lot notes before assigning a report to an assay.

Research use only. Not for human or veterinary use. No medical, cosmetic, or performance claims are made or implied.

The 10 mg fill is a separate catalogue listing: SS-31 10 mg.