Glossary · 2026-09-24
Scientific lead: Alice Kay, Ph.D.
GHSR-1a, ghrelin-receptor laboratory term
GHSR-1a is the growth hormone secretagogue receptor type 1a, the functional receptor for ghrelin. It is a G protein-coupled receptor. Papers distinguish it from GHSR-1b, a truncated splice variant that is discussed as lacking the same signaling competence. They also distinguish it from the GHRH receptor. A ligand at GHSR-1a is not, by that assignment, a GHRH analogue.
On this catalog, ipamorelin is the pentapeptide filed as a GHSR ligand. The class note is GHSR ligands. The live vials are ipamorelin 10 mg and the CJC-1295 (no DAC) / ipamorelin fill, which also contains a GHRH-analogue sequence.
Frequently asked questions
- Is GHSR-1a the same receptor as the GHRH receptor?
- No. GHSR-1a is the ghrelin receptor. The GHRH receptor is a different GPCR. Sermorelin, tesamorelin, and CJC-1295 without DAC are discussed at the GHRH receptor. Ipamorelin is discussed at GHSR-1a.
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