What is SS-31? Mitochondrial tetrapeptide

> Research-use notice: This article is educational laboratory context only. It is not medical advice. No dosing, administration, or human-use guidance is provided. BlueNex Labs research-use-only products are not intended for human or veterinary use.

SS-31 is a synthetic tetrapeptide also discussed in the literature as elamipretide and as a Szeto–Schiller peptide. Published descriptions treat it as a short, mitochondria-targeted sequence used to probe inner-membrane and electron-transport models. This page is a research guide. The catalog fills, 10mg and 50mg, sit on the SS-31 product page. A 10mg report does not document a 50mg vial.

Structure

Laboratory descriptions of SS-31 usually emphasize:

• A four-residue sequence, much shorter than mitochondrial-derived peptides such as MOTS-c

• Aromatic and basic residues that papers associate with affinity for cardiolipin in the inner mitochondrial membrane

• Identity confirmed by mass spectrometry on the lot report, not by the common name alone

• HPLC or UPLC purity on that same report when one is published

The vial label and the Certificate of Analysis are the identity record. This article does not replace them.

Mechanisms discussed in research settings

Papers place SS-31 in experimental mitochondrial work, including:

• Inner-membrane and cardiolipin interaction models

• Electron-transport and membrane-potential assays in isolated mitochondria or cell systems

• Comparisons with other cellular-energy reagents, which are different molecules

• The broader mitochondrial-peptide reading list, beside MOTS-c and NAD+ cofactor work

Those models stay inside the assay that generated them. A mechanism note is not a use instruction, and it is not a statement about an authorized medicine.

What this guide is not

It is not the shop listing, not a COA library, and not a protocol. MOTS-c has its own note: What is MOTS-c? Mitochondrial research. The class overview is Mitochondrial peptides as a research class. Stocked cellular-energy SKUs are indexed under Mitochondrial Research Peptides Canada.

Documentation and RUO

Open the certificates library when a lot for this SKU is published. How to read a peptide Certificate of Analysis explains HPLC versus mass spectrometry.

Research-use only. Not for human or veterinary use. No administration guidance is provided.