BPC-157 vs TB-500: Research Comparison

Research-use notice: This page records catalogue differences only: sequences, receptor classes, fill sizes, and Certificate of Analysis rows. It is not a protocol. It is not medical or veterinary advice, and it does not rank materials for personal use. BlueNex Labs materials are research use only. Research-use-only labelling is not a Health Canada authorization and it does not create a Drug Identification Number.

BPC-157 and TB-500 are cited next to each other often enough that a blend vial looks like one molecule. It is two sequences in one glass, and the single-peptide listings are different glasses again. This page separates the chains, the catalogue sizes, and the certificate rows. For the paired literature note, which explains why methods papers mention the names together, see BPC-157 and TB-500 as paired lab topics. Read that note for the citation pattern. Read this page for the lot difference. Neither page is a protocol.

Fifteen residues versus a thymosin fragment

BPC-157 is the synthetic pentadecapeptide Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, abbreviated GEPPPGKPADDAGLV, with a free-peptide mass near 1419 daltons. Sikiric and colleagues introduced that partial sequence of a gastric protein as BPC in the Journal of Physiology (Paris) in 1993 (volume 87, pages 313-327). For the glossary entry, see pentadecapeptide. For the compound guide, see What is BPC-157?. Fifteen residues from a gastric protein are not a thymosin, and a thymosin certificate cannot confirm them.

TB-500, on this catalogue, is named as a synthetic fragment modelled on a region of thymosin beta-4, the 43-residue actin-binding polypeptide. Fragment papers discuss the acetylated heptapeptide Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln, corresponding to residues 17-23 of thymosin beta-4, as an actin-binding motif. That heptapeptide is the sequence the fragment literature is usually pointing at when it uses the TB-500 name. It is not the full 43-residue chain, and it is not thymosin alpha-1. For the compound guide, see What is TB-500?. For the family split with thymosin alpha-1, see a separate comparison. The single-peptide TB-500 purity report is at the TB-500 10 mg certificate row. This page does not promote the heptapeptide string to a lot specification. The observed mass on that certificate is the identity check.

Why the names share a sentence

Methods papers that place the gastric pentadecapeptide beside a thymosin beta-4 fragment are usually asking a cell-migration or cytoskeleton question in a stated model. The Wolverine note is the map of that habit. A habit in the secondary literature is not a combined sequence, and it is not a reason to file a blend area percent as two identities. Actin-binding language belongs to the thymosin fragment literature. It does not transfer to GEPPPGKPADDAGLV. Gastric-protein language does not transfer to the fragment.

Four inventory lines

Count the SKUs before you count the peptides. BPC-157 10 mg is one lot. TB-500 10 mg is another. The 5 mg/5 mg blend is a third. The 10 mg/10 mg blend is a fourth. The public library anchors each of those four fills on its own row. The 5 mg/5 mg PDF documents that split only. It does not document the larger blend, and it does not document either single-peptide cake. Read the TB-500 10 mg certificate row for that purity file. How to read a peptide COA is the method when a file exists. A missing file stays missing.

The cellular category hub also lists GHK-Cu, thymosin alpha-1, and melanocortin ligands. Those are other classes. A BPC-157 mass near 1419 daltons will not match a copper tripeptide or a 28-residue thymic peptide. Use the disagreement. Do not average it away with a category name.

Receiving

Canadian orders pay by Interac e-Transfer and move on Canada Post Xpresspost. For the long form, see Canada laboratory procurement. Write the slug, the milligram split, and the lot on one line before the material enters a study file. Research use only. Not for human or veterinary use.