Comparison · 2026-09-24
Scientific lead: Alice Kay, Ph.D.
BPC-157 vs TB-500: Research Comparison
Research-use notice: This page compares sequences, receptor classes, and catalog records. It is not medical or veterinary advice, and it does not rank materials for personal use. BlueNex Labs materials are research-use only. Research-use-only labeling is not a Health Canada authorization and it does not create a Drug Identification Number.
BPC-157 and TB-500 are cited next to each other often enough that a blend vial looks like one molecule. It is two sequences in one glass, and the single-peptide listings are different glasses again. This page separates the chains, the catalog sizes, and the certificate rows. The paired literature note, which explains why methods papers mention the names together, is BPC-157 and TB-500 as paired lab topics. Read that note for the citation pattern. Read this page for the lot difference. Neither page is a protocol.
Fifteen residues versus a thymosin fragment
BPC-157 is the synthetic pentadecapeptide Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, abbreviated GEPPPGKPADDAGLV, with a free-peptide mass near 1419 daltons. Sikiric and colleagues introduced that partial sequence of a gastric protein as BPC in the Journal of Physiology (Paris) in 1993 (volume 87, pages 313-327). The glossary entry is pentadecapeptide. The compound guide is What is BPC-157?. Fifteen residues from a gastric protein are not a thymosin, and a thymosin certificate cannot confirm them.
TB-500, on this catalog, is named as a synthetic fragment modeled on a region of thymosin beta-4, the 43-residue actin-binding polypeptide. Fragment papers discuss the acetylated heptapeptide Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln, corresponding to residues 17-23 of thymosin beta-4, as an actin-binding motif. That heptapeptide is the sequence the fragment literature is usually pointing at when it uses the TB-500 name. It is not the full 43-residue chain, and it is not thymosin alpha-1. The compound guide is What is TB-500?. The family split with thymosin alpha-1 is a separate comparison. Because the single-peptide TB-500 lot report is not in the library, this page does not promote the heptapeptide string to a lot specification. The observed mass on a future certificate is the identity check.
Why the names share a sentence
Methods papers that place the gastric pentadecapeptide beside a thymosin beta-4 fragment are usually asking a cell-migration or cytoskeleton question in a stated model. The Wolverine note is the map of that habit. A habit in the secondary literature is not a combined sequence, and it is not a reason to file a blend area percent as two identities. Actin-binding language belongs to the thymosin fragment literature. It does not transfer to GEPPPGKPADDAGLV. Gastric-protein language does not transfer to the fragment.
| Record | BPC-157 | TB-500 |
|---|---|---|
| Sequence or length | 15 residues, GEPPPGKPADDAGLV | Catalogued as a thymosin beta-4 fragment; fragment literature discusses the acetylated heptapeptide Ac-LKKTETQ |
| Molecular class | Synthetic partial sequence of a gastric protein | Synthetic fragment associated with thymosin beta-4 |
| Receptor or target class | No single named GPCR class on this catalog; discussed in cell-signaling models | Discussed against actin and cell-migration models, not as a melanocortin or incretin ligand |
| Catalog sizes | 10 mg alone. Blends: 5 mg/5 mg and 10 mg/10 mg. | 10 mg alone, plus the same two blend fills. |
| COA | certificates#bpc-157-10mg for the single 10 mg vial. | No single-peptide anchor on the September 20, 2026 review. The blend anchor is certificates#bpc-157-tb-500-5mg5mg only. |
Four inventory lines
Count the SKUs before you count the peptides. BPC-157 10 mg is one lot. TB-500 10 mg is another. The 5 mg/5 mg blend is a third. The 10 mg/10 mg blend is a fourth. The public library, as reviewed September 20, 2026, anchors the BPC-157 10 mg vial and the 5 mg/5 mg blend. It does not anchor TB-500 alone or the 10 mg/10 mg blend. The 5 mg/5 mg PDF therefore documents that split only. It does not document the larger blend, and it does not document either single-peptide cake. How to read a peptide COA is the method when a file exists. A missing file stays missing.
The cellular category hub also lists GHK-Cu, thymosin alpha-1, and melanocortin ligands. Those are other classes. A BPC-157 mass near 1419 daltons will not match a copper tripeptide or a 28-residue thymic peptide. Use the disagreement. Do not average it away with a category name.
Receiving
Canadian orders pay by Interac e-Transfer and move on Canada Post Xpresspost. The long form is Canada laboratory procurement. Write the slug, the milligram split, and the lot on one line before the material enters a study file. Research-use only. Not for human or veterinary use.
Frequently asked questions
- Are BPC-157 and TB-500 the same family?
- No. BPC-157 is a 15-residue partial sequence from a gastric protein. TB-500 on this catalog is named as a thymosin beta-4 fragment. The sequences are not interchangeable, even when a blend vial contains both.
- Does the blend certificate cover the single-peptide vials?
- No. The published blend report documents the 5 mg/5 mg lot. It does not document BPC-157 10 mg, TB-500 10 mg, or the 10 mg/10 mg blend. BPC-157 10 mg has its own anchor. TB-500 10 mg did not, on the September 20, 2026 review.
- What is the paired literature note for?
- The Wolverine literature note explains why methods papers cite the two names in the same cell-migration conversation. It is not a use instruction, and it does not merge the sequences.
Research-use only. BlueNex Labs does not provide medical or veterinary advice. Confirm your institution’s policies before purchase.